TRABD2A Polyklonale Antilichaam, APC-Cy5,5 Vervoeging

Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation. [COFACTOR] Divalent metal cations. Manganese or cobalt.

C2orf89; CB089_HUMAN; UPF0632 protein C2orf89.

Extracellular

Human, Mouse, Rat

201-300/505

TRABD2A

APC-Cy5.5

KLH conjugated synthetic peptide derived from human C2orf89

WB, IF (IHC-P)

Purified by Protein A.

650nm/694nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.