TRADD Antilichaam

The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.

71609

Q15628

Human, Mouse, Rat

Recombinant protein of mouse TRADD

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle, Growth Factors, Immunology, Signal Transduction

Affinity purification

MCF7

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 34kDa

IgG

TRADD

Jurkat

Tumor necrosis factor receptor type 1-associated DEATH domain protein

Mus musculus

Tumor necrosis factor receptor type 1-associated DEATH domain protein, TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain, TRADD

WB, IHC, IF

Liquid