![TRAIL Antilichaam [SB91c]](/_ipx/q_80/productPlaceholder.webp)
TRAIL Antilichaam [SB91c]
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the TNF family of cytokines. This type II transmembrane protein is expressed by several cytotoxic immune cells, including natural killer cells and activated T cells, and is selective for tumorigenic and virally infected cells. TRAIL can bind to DR4 and DR5 receptors on target cells which facilitates recruitment of numerous signaling proteins to form a death-inducing signaling complex. This signaling complex is then believed to propagate the apoptotic signal through the recruitment and activation of caspase-8. Numerous studies have identified TRAIL as a potent apoptotic factor in a variety of human cancer cell lines, but this cytokine does not appear to affect normal cell lines. Therefore, the selectivity and anti-tumorigenic properties of TRAIL make it an intriguing and potentially therapeutic agent in the treatment of cancer.
8743
P50591
P50591
• Mouse
Human
Recombinant TRAIL
• Monoclonal
[SB91c]
Unconjugated
Primary Antibodies
Cancer, Immunology
0.5 mg/mL
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
None
Blue Ice
Store vial at 2-8˚ C
IgG2b
TRAIL
TRAIL Antibody [SB91c] for use in ELISA assays.
TNFSF10
Tumor necrosis factor (ligand) superfamily, member 10
Homo sapiens
CD253, Apo-2 ligand, Apo-2L, TNFSF10
WB, IHC-Fr, Flow, IP
Liquid
Beschrijving
TRAIL Antilichaam [SB91c] Beschikbaar in 0.5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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