TRAIL Recombinant Proteïne

TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic "death domain”, which activates the cell’s apoptotic machinery. Recombinant murine soluble TRAIL is a 174 amino acid polypeptide (20.0 kDa), consisting of the TNF homologous portion of the extracellular domain of the full length TRAIL protein.

22035

P50592

NP_033451.1

Recombinant Proteins

E. coli

Other

Room Temp

The lyophilized TRAIL recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted TRAIL is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing TRAIL recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Tumor necrosis factor (ligand) superfamily, member 10

Mus musculus

TL2, Ly81, Trail, APO-2L, AI448571, A330042I21Rik, Tumor necrosis factor ligand superfamily member 10, TNF-related apoptosis-inducing ligand, Protein TRAIL

Murine

6678431

Lyophilized