Trandolapril-d3

Trandolapril-d3 is the deuterium labeled Trandolapril. Trandolapril (RU44570) is a nonsulfhydryl proagent that is hydrolysed to the active diacid Trandolaprilat. Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI).

12352005

Angiotensin-converting Enzyme (ACE) ; Isotope-Labeled Compounds

Metabolic Enzyme/Protease; Others

Cardiovascular Disease

[H][C@@](CCCC1)(N2C([C@@H](N[C@H](CCC3=CC=CC=C3)C(OCC)=O)C([2H])([2H])[2H])=O)[C@]1(C[C@H]2C(O)=O)[H]

C24H31D3N2O5

433.56

[1]Peters DC, et al. Trandolapril. An update of its pharmacology and therapeutic use in cardiovascular disorders. Drugs. 1998 Nov;56 (5) :871-93.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W744298/

Isotope-Labeled Compounds

No Development Reported