TRAP-14-amide

141923-36-6

Protease-activated Receptor, MMP, Integrin

Cytoskeletal Signaling, GPCR/G Protein, Proteases/Proteasome

TRAP-14 amide is a protease-activated receptor (PAR) activating peptide and acts as a PAR agonist, with an EC50 of 24 μM. It induces significant platelet aggregation via ADP and MMP-2 dependent pathways and is insensitive to Aspirin. Additionally, TRAP-14 amide effectively increases the surface expression of glycoprotein (GP) Ib and GPIIb/IIIa, as well as the release of ADP.

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C81H119N21O22

1738.94

Ice Packs

-20°C