TRBP1 Antilichaam

TRBP1 Antibody: The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1α (EF-1α ), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB) . TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.

6894

Q13395

NP_005637

Human, Mouse

Unconjugated

Primary Antibodies

Infectious Disease

TRBP1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1212 - 3T3 Cell Lysate

1 mg/mL

TRBP1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TRBP1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

TARBP1

TAR (HIV-1) RNA binding protein 1

Homo sapiens

Gatignol A, Buckler-White A, Berkhout B, et al. Characterization of a human TAR REN-binding protein that activates the HIV-1 LTR. Science 1991; 251:1597-1600.

Wu-Baer F, Lane WS, and Gaynor RB. Identification of a group of cellular cofactors that stimulate the binding of RNA polymerase II and TRP-185 to human immunodeficiency virus 1 TAR RNA. J. Biol. Chem.1996; 271:4201-8.

TRBP1 Antibody: TRM3, TRP185, TRP-185, TRM3, Probable methyltransferase TARBP1, TAR RNA-binding protein 1

ELISA, WB

110825988

Liquid