Trefoil Factor 3 Recombinant eiwit

The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are secreted in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF-3 is expressed by goblet cells and in the uterus, and has also been shown to express in certain cancers, including colorectal, hepatocellular, and in biliary tumors. TFF3 may be useful as a molecular marker for certain types of cancer, but its role, if any, in tumorigenesis is unknown. TFF3 also promotes airway epithelial cell migration and differentiation. Recombinant human TFF3 is a 13.2 kDa homodimeric protein consisting of two 59 amino acid chains, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.

7033

Q07654

NP_003217.3

Recombinant Proteins

E. coli

Homeostasis

Room Temp

The lyophilized Trefoil Factor 3 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted Trefoil Factor 3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing Trefoil Factor 3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Trefoil factor 3 (intestinal)

Homo sapiens

ITF, P1B, TFI, ITF, Trefoil factor 3, Intestinal trefoil factor, hITF

Human

281485608

Lyophilized