TRIB2 Mouse Monoclonal Antibody [Kloon ID: LBI8D11]

This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.

Carrier-free (BSA/glycerol-free) TRIB2 mouse monoclonal antibody, clone LBI8D11

C5FW; GS3955; TRB2

Homo sapiens tribbles pseudokinase 2 (TRIB2), transcript variant 1, mRNA.

28951

Q92519

Unconjugated

WB 1:1000~2000, IHC 1:50, IF 1:50, FLOW 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Protein Kinase

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

TRIB2

https://www.ncbi.nlm.nih.gov/gene/?term=28951

https://www.uniprot.org/uniprot/Q92519