TRIB3 (NM 021158) Humaan Recombinant Proteïne

The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]

Purified recombinant protein of Human tribbles homolog 3 (Drosophila) (TRIB3), Met1-Leu200, with N-terminal His tag, expressed in E. coli, 50ug

C20orf97; NIPK; SINK; SKIP3; TRB3

57761

Q96RU7

NM_021158

20p13

E. coli

N-His

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

50mM Tris, 8M Urea, pH8.0

Druggable Genome, Protein Kinase, Transcription Factors

22.3 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

TRIB3

Human

NP_066981

https://www.ncbi.nlm.nih.gov/gene/57761

https://www.uniprot.org/uniprot/Q96RU7

https://www.ncbi.nlm.nih.gov/nuccore/NM_021158

https://www.ncbi.nlm.nih.gov/nuccore/NP_066981