Triglycidylisocyanuraat-d15

Triglycidyl Isocyanurate-d15 is the deuterium labeled Triglycidyl isocyanurate. Triglycidyl isocyanurate (TGIC; Teroxirone) is a triazene triepoxide with antiangiogenic and antineoplastic activities. Triglycidyl isocyanurate inhibits the growth of non-small-cell-lung cancer cells via p53 activation. Triglycidyl isocyanurate induces cell apoptosis. Triglycidyl isocyanurate can be used for cancer research[1][2].

2732873-64-0

12352005

Apoptosis; Isotope-Labeled Compounds; MDM-2/p53

Apoptosis; Others

Cancer-programmed cell death

Cancer

O=C(N(C1=O)C([2H])(C2(C([2H])(O2)[2H])[2H])[2H])N(C(N1C([2H])(C3(C([2H])(O3)[2H])[2H])[2H])=O)C([2H])(C4(C([2H])(O4)[2H])[2H])[2H]

C12D15N3O6

312.36

[1]Yu-Ling Ni, et al. Teroxirone motivates apoptotic death in tumorspheres of human lung cancer cells. Chem Biol Interact. 2018 Aug 1;291:137-143.|[2]Seung-Hun Kim, et al. Teroxirone suppresses growth and motility of human hepatocellular carcinoma cells.Biomed Pharmacother. 2018 Mar;99:997-1008

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W750535/

Isotope-Labeled Compounds

No Development Reported