TRIM24 Antilichaam - middengebied: Biotine (ARP34449 P050-Biotine)

Tripartite motif containing 24

PTC6, TF1A, TIF1, RNF82, TIF1A, hTIF1, TIF1ALPHA

8805

O15164

NP_056989

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human TRIM24

The exact function of TRIM24 remains unknown. The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

UBC; SUMO2; SUMO3; TRIM33; TP53; SUMO1; RNF2; RNF181; RNF141; ESR2; BRCA1; SF3B1; SF3B2; SNRPA; NONO; CDK12; NCOA1; TRIM8; NR3C2; ESR1; HIST1H3E; HIST2H4B; HIST4H4; HIST1H3F; HIST2H4A; HIST1H4L; HIST1H4E; HIST1H4B; HIST1H4H; HIST1H4C; HIST1H4J; HIST1H4K

Biotin

Polyclonal Antibody

WB

Affinity Purified

TRIM24 is supported by BioGPS gene expression data to be expressed in HeLa

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 82%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

117kDa

Yondola, M.A. (2007) J. Virol. 81 (8), 4264-4271

Wet Ice

1050

TRIM24

TRIM24

Rabbit

Transcription intermediary factor 1-alpha

NM_015905

QQPSISHQQPPPRLINFQNHSPKPNGPVLPPHPQQLRYPPNQNIPRQAIK