TRIM63 Antilichaam - middengebied: Biotine (ARP43365 P050-Biotine)

Tripartite motif containing 63, E3 ubiquitin protein ligase

IRF, SMRZ, MURF1, MURF2, RNF28

84676

Q969Q1

NP_115977

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human TRIM63

This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.

UBE2D3; UBE2D1; UBC; TRIM63; USP37; ANKIB1; EPN1; ATXN3; EPS15; DCAF6; LMCD1; ANKRD1; NOMO1; GMEB1; NEBL; PIAS3; MRPL19; MYOT; PIAS2; SQSTM1; TCAP; PIAS1; UXT; UQCRC1; TTN; TNNI3; TNNI2; TNNI1; GFM1; TRIM55; MRPL41; MYOZ1; NEB; NDUFA1; MYBPC3; MYBPC1; EIF

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

40kDa

Wet Ice

353

TRIM63

TRIM63

Rabbit

E3 ubiquitin-protein ligase TRIM63

NM_032588

EQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTEQ