TRPC6 Antilichaam

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2) .

7225

Q61143

NP_004612.2

Human, Mouse, Rat

TRPC6 antibodypeptide Corresponding to the amino terminal sequence derived from mouse TRPC6.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

100 kDa

This antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western Blot: 1:500~1:1000

TRPC6

Transient receptor potential cation channel, subfamily C, member 6

Peptide Corresponding to the amino terminal sequence derived from mouse TRPC6.

Koichiro Kuwahara et al. (2006) J Clin Invest. 116 (12) : 3114–3126. Mark Estacion et al. (2006) J Physiol. 2006, 572 (Pt 2) : 359–377. Maria A et al. (2006) Proc Natl Acad Sci U S A. 103 (44) : 16586–16591.

TRP6, FSGS2, TRP6, FLJ11098

WB

5730102

Liquid