
TSC1 Polyklonale Antilichaam, APC-vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each other forming a cystoplasmic complex. Hamartin interacts with the ezrin-radixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney.
Hamartin; kiaa0243; LAM; TSC; TSC1; Tsc1 gene; TSC1_HUMAN; Tuberous sclerosis 1; Tuberous sclerosis 1 protein.
7248
Cytoplasm, Cell membrane
• Rabbit
701-800/1164
TSC1
• Polyclonal
• IgG
APC
KLH conjugated synthetic peptide derived from human Hamartin
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purified by Protein A.
650nm/660nm
1µg/µl
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
7248
Human, Mouse, Rat
Beschrijving
TSC1 Polyklonale Antilichaam, APC-vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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