TSFM-antilichaam - middengebied: HRP (ARP31455_P050-HRP)

Ts translation elongation factor, mitochondrial

EFTS, EFTSMT

10102

P43897

NP_005717

Human, Mouse, Rat, Cow, Guinea Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human TSFM

The TSFM protein is a mitochondrial translation elongation factor. Synthesis of the 13 mitochondrial-encoded proteins occurs on a dedicated mitochondrial translation apparatus similar to that found in prokaryotes and requires, in addition to the tRNAs and rRNAs encoded in mtDNA, the concerted action of several translation factors and a large number of mitochondrial ribosomal proteins, all of which are encoded by nuclear genes.Synthesis of the 13 mitochondrial-encoded proteins occurs on a dedicated mitochondrial translation apparatus similar to that found in prokaryotes and requires, in addition to the tRNAs and rRNAs encoded in mtDNA, the concerted action of several translation factors and a large number of mitochondrial ribosomal proteins, all of which are encoded by nuclear genes. The TSFM gene encodes a mitochondrial translation elongation factor (Smeitink et al., 2006 [PubMed 17033963]) .[supplied by OMIM].

UBC; SUMO2; LIG4; C1QBP; MRRF; ACOT13; CDV3; MTRNR2L1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

TSFM is strongly supported by BioGPS gene expression data to be expressed in 721_B, HeLa, MCF7 There is BioGPS gene expression data showing that TSFM is expressed in HEK293T

0.5 mg/ml

Cow: 86%; Guinea Pig: 86%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

38kDa

Smeitink, J.A., (2006) Am. J. Hum. Genet. 79 (5), 869-877

Wet Ice

346

TSFM

TSFM

Rabbit

Elongation factor Ts, mitochondrial

NM_005726

GTMMHCQTLKDQPSAYSKGFLNSSELSGLPAGPDREGSLKDQLALAIGKL