TSHZ1 Antilichaam

TSHZ1 Antibody: The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. TSHZ1 has been found to be required for axial skeleton, soft palate and middle ear development in mice and may be involved in a common pathway with the Hox genes. Both TSHZ1 and the related protein TSHZ3 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4.

10194

Q6ZSZ6

NP_005777

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Stem Cell

TSHZ1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1288 - A20 Cell Lysate

1 mg/mL

TSHZ1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TSHZ1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

TSHZ1

Cat. No. 17-208 - A-20 Cell Slide

Teashirt zinc finger homeobox 1

Homo sapiens

Caubit X, Core N, Boned A, et al. Vertebrate orthologues of the Drosophila region-specific patterning gene teashirt. Mech. Dev. 2000; 91:445-8.

Santos JS, Fonseca NA, Vieira CP, et al. Phylogeny of the Teashirt-related zinc finger (tshz) gene family and analysis of the developmental expression of tshz2 and tshz3 in the zebrafish. Dev. Dyn. 2010; 239:1010-8.

Core N, Caubit X, Metchat A, et al. Tshz1 is required for axial skeleton, soft palate and middle ear development in mice. Dev. Biol. 2007; 308:407-20

Kajiwara Y, Akram A, Katsel P, et al. FE65 binds teashirt, inhibiting expression of the primate-specific caspase-4. PLoS One 2009; 4:e5071.

TSHZ1 Antibody: CAA, TSH1, NY-CO-33, SDCCAG33, Teashirt homolog 1, Antigen NY-CO-33

ELISA, WB, ICC, IF

38201677

Liquid