TSHZ2 Antilichaam

TSHZ2 Antibody: The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. In mice, the known three TSHZ proteins are expressed in distinct patterns in the developing and adult brain, suggesting that they play a role in the establishment of regional identity and specification of cell types within the brain. Recent experiments have shown that the expression of TSHZ2 is frequently downregulated in most breast and prostate cancers and its promoter was unmethylated in virtually all cases, suggesting this family of proteins may also be involved in carcinogenesis.

128553

Q9NRE2

NP_775756

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Stem Cell

TSHZ2 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1288 - A20 Cell Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Pig: (88%)

TSHZ2 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TSHZ2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

TSHZ2

Cat. No. 17-208 - A-20 Cell Slide

Teashirt zinc finger homeobox 2

Homo sapiens

Caubit X, Core N, Boned A, et al. Vertebrate orthologues of the Drosophila region-specific patterning gene teashirt. Mech. Dev. 2000; 91:445-8.

Santos JS, Fonseca NA, Vieira CP, et al. Phylogeny of the Teashirt-related zinc finger (tshz) gene family and analysis of the developmental expression of tshz2 and tshz3 in the zebrafish. Dev. Dyn. 2010; 239:1010-8.

Caubit X, Tiveron MC, Cremer H, et al. Expression patterns of the three Teashirt-related genes define specific boundaries in the developing and postnatal mouse forebrain. J. Comp. Neurol. 2005; 486:76-88.

Yamamoto M, Cid E, Bru S, et al. Rare and frequent promoter methylation, respectively, of TSHZ2 and 3 genes that are both downregulated in expression in breast and prostate cancers. PLoS ONE 2011; 6:e17149.

TSHZ2 Antibody: TSH2, ZABC2, ZNF218, OVC10-2, C20orf17, TSH2, Teashirt homolog 2, Ovarian cancer-related protein 10-2

ELISA, WB, IF

153945734

Liquid