TSSC4 Antilichaam - middengebied: Biotine (ARP52089_P050-Biotine)

Tumor suppressing subtransferable candidate 4

10078

Q9Y5U2-2

Human

The immunogen is a synthetic peptide directed towards the middle region of Human TSSC4

This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. Several transcript variants encoding two different isoforms have been found for this gene.

TCF4; CEP76; GMCL1; RNF31; TRAF2; TRAF1; REL; KPNA3; GOLGA2; UBC; WDR70; APP; TERF2IP; TAB1; Prpf8; UBA1; SPTAN1

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

29kDa

Wet Ice

265

TSSC4

TSSC4

Rabbit

Protein TSSC4

FTKPVRGVEARHERKRVLGKVGEPGRGGLGNPATDRGEGPVELAHLAGPG