TSTA3 Antilichaam - N-terminaal gebied: Biotine (ARP58679 P050-Biotine)

Tissue specific transplantation antigen P35B

FX, P35B, TSTA3, SDR4E1

7264

Q13630

NP_003304

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human TSTA3

Tissue specific transplantation antigen P35B is a NADP (H) -binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.Tissue specific transplantation antigen P35B is a NADP (H) -binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.

UBC; COASY; EFHD2; PPME1; GLRX3; GMPS; RCN1; RBBP7; BAG3; RIOK2; ID2; DNAJC9; DSTN; NEDD4

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

TSTA3 is strongly supported by BioGPS gene expression data to be expressed in 721_B, HeLa TSTA3 is supported by BioGPS gene expression data to be expressed in MCF7

0.5 mg/ml

Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

35kDa

Roos, C., (2002) J. Biol. Chem. 277 (5), 3168-3175

Wet Ice

321

TSTA3

TSTA3

Rabbit

GDP-L-fucose synthase

NM_003313

MGEPQGSMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTD