TTYH1 Antilichaam

TTYH1 Antibody: TTYH1 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH1 is a Ca2+-independent, volume-sensitive large conductance chloride (Cl-) channel. TTYH1 is primarily expressed in neural tissue and upregulated in astrocytoma, glioma, and several other cancers. Recent experiments have shown that TTYH1 is an integral endoplasmic reticulum (ER) membrane protein involved in cell proliferation and is thought to play an essential role in embryonic cell growth, possibly through the Ca2+ storage/release process in ER membranes during early development.

57348

Q9H313

NP_001005367

Human

Unconjugated

Primary Antibodies

Stem Cell

TTYH1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1207 - Raji Cell Lysate

1 mg/mL

TTYH1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TTYH1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

TTYH1 antibody is human specific. Multiple isoforms of TTYH1 are known to exist.

TTYH1

Cat. No. 17-007 - Raji Cell Slide

Tweety homolog 1 (Drosophila)

Homo sapiens

Campbell HD, Kamei M, Caludianos C, et al. Human and mouse homologues of the Drosophila melanogaster tweety (tty) gene: a novel gene family encoding predicted transmembrane proteins. Genomics 2000; 68:89-92.

Matthews CA, Shaw JE, Hooper JA, et al. Expression and evolution of the mammalian brain gene Ttyh1. J. Neurochem. 100:693-707

Kumada T, Yamanaka Y, Kitano A, et al. Ttyh1, a Ca2+-binding protein localized to the endoplasmic reticulum, is required for early embryonic development. Dev. Dyn. 2010; 239:2233-45.

TTYH1 Antibody: Protein tweety homolog 1, hTTY1

ELISA, WB, ICC

53831989

Liquid