TUBA1/3/4 (fosfo Tyr272) Antilichaam

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species.

7846;10376;84790;113457;7278;112714;7277

Q71U36; P68363; Q9BQE3; Q13748; Q6PEY2; P68366

NP_001257328.1

Human, Mouse, Rat

TUBA1/3/4 (phospho Tyr272) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 272 (A-T-Y (p) -A-P) derived from Human TUBA1/3/4.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

50-55 kDa

IgG

The antibody detects endogenous levels of TUBA1/3/4 only when phosphorylated at tyrosine 272.

Western Blot: 1:500~1:1000

TUBA1A, TUBA1B, TUBA1C

Tubulin alpha 1a, tubulin alpha 1b, tubulin alpha 1c

Homo sapiens

Adler A.J., Bioorg. Med. Chem. 9:1967-1976 (2001) .

Sugano S., Nat. Genet. 36:40-45 (2004) .

Venter J.C., Submitted (JUL-2005) .

TBA1, TBA1A, TBA4A, TUBA1

WB

17986283

Liquid