Tucatinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
937263-43-9
Irbinitinib, ONT-380, ARRY-380
C13368-5mg
HER2
Protein Tyrosine Kinase
CC1=C (C=CC (=C1) NC2=NC=NC3=C2C=C (C=C3) NC4=NC (CO4) (C) C) OC5=CC6=NC=NN6C=C5
C26H24N8O2
Tucatinib (Irbinitinib, ONT-380, ARRY-380) is an oral, potent, selective, reversible and ATP-competitive small-molecule inhibitor of ErbB-2 (also called HER2) with IC50s of 8 nM and 7 nM for ErbB-2 and p95 HER2, respectively in cell-based assays, showing ~500-fold selective for HER2 vs EGFR. It has potential antineoplastic activity.
2 years -80 in solvent
Beschrijving
Tucatinib Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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