Tucotuzumabcelmoleukin
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Tucotuzumab celmoleukin (EMD 273066) is an immunocytokine fusion agent targeting the epithelial cell adhesion molecule (EpCAM) . Tucotuzumab celmoleukin binds to EpCAM and delivers IL-2 to the tumor microenvironment, which can activate cytotoxic effector cells, such as CD8+ T cells and natural killer (NK) cells. Tucotuzumab celmoleukin is promising for research of EpCAM-positive cancers, such as colorectal cancer and prostate cancer[1][2].
339986-90-2
EMD 273066; huKS-IL2
12352203
Interleukin Related
Immunology/Inflammation
Cancer-programmed cell death
Cancer
[Tucotuzumabcelmoleukin]
[1]Eyvazi S, et al. Antibody Based EpCAM Targeted Therapy of Cancer, Review and Update. Curr Cancer Drug Targets. 2018;18 (9) :857-868.|[2]Wang Z, et al. High-Affinity Fully Human Anti-EpCAM Antibody with Biased IL-2 Exhibits Potent Antitumor Activity. Biomolecules. 2024 Nov 2;14 (11) :1399.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991214/
Inhibitory Antibodies
Phase 3
Beschrijving
Tucotuzumab celmoleukin (EMD 273066) is an immunocytokine fusion agent targeting the epithelial cell adhesion molecule (EpCAM) . Tucotuzumab celmoleukin binds t
Specificaties
Recent bekeken producten
Human Mast Cells - Dermis
ABC-TC105W
1 Vial
CYP1A2 Inhibitor Screening Assay
MA-0389
200 Well
Culture Medium for Immortalized Human Parathyroid Cells
AFG-ELL-2645-01
100 mL
Immortalized Human Parathyroid Cells
AFG-ELL-2055
> 1x 10^6 Cells / Vial
1,4- Dioxane Pure
1041330 500
500 mL
EPS8 Antibody (N-term) [APR32555G]
APR32555G-01
50 µL
Prestained Protein Ladder (25-300 kDa)
CRG1114
250 µL
Rat IgG Lyophilized
B2013903
25 mg
Recent gezochte producten
Hsa-miR-1258 mimic
HY-R00162-01
5 nmol
Hsa-miR-4258 mimic
HY-R00937-01
5 nmol
hsa-miR-1258 miRNA Mimic
MBS8298831-01
5 nmol
hsa-miR-4258 miRNA Mimic
MBS8299087-01
5 nmol
hsa-miR-1258 miRNA Agomir
MBS8311479-01
5 nmol
Hsa-miR-1258 miRNA Mimic
CMH0784-01
5 nmol
Hsa-miR-4258 miRNA Mimic
CMH1040-01
5 nmol
Hsa-miR-4258 miRNA Agomir
CMJ1040-01
5 nmol