TUG-antilichaam [4A11A6G11]

The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.

79058

Q9BZE9

Q9BZE9

Mouse

Ni-NTA purified truncated recombinant TUG expressed in E. Coli strain BL21 (DE3) .

4A11A6G11

Unconjugated

Primary Antibodies

Growth Factors

Antibody is purified by protein A affinity chromatography and resuspended in PBS with 0.2%BSA, 0.09% sodium azide.

Batch dependent

Purified antibody in PBS containing 0.03% sodium azide.

None

Blue Ice

Mouse TUG monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1

ASPSCR1

Alveolar soft part sarcoma chromosome region, candidate 1

Homo sapiens

Nature 2003,425:727 - 733.

ASPL, RCC17, TUG, UBXD9, UBXN9, Alveolar soft part sarcoma chromosomal region candidate gene 1 proteinTUG, ASPL, ASPS, ASPCR1

ELISA, WB

74717746