Twist2 Antilichaam

Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

117581

Q8WVJ9

NP_476527.1

Human, Mouse, Rat

Twist2 antibody was raised against a peptide sequence around aa.26~30 (P-K-R-F-G) derived from Human Twist2.

Unconjugated

Primary Antibodies

Stem Cell

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

18 kDa

This antibody detects endogenous level of total Twist2 protein.

Western Blot: 1:500~1:1000

TWIST2

Twist family bHLH transcription factor 2

Homo sapiens

Lee M. S., Lowe G., Flanagan S., Kuchler K., Glackin C. A. Bone 27:591-602 (2000)

FFDD3, DERMO1, SETLSS, bHLHa39, MGC117334

WB

17981708

Liquid