TXB4
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
TXB4 is a brain-permeable human monoclonal antibody (mAb) targeting CD71. TXB4 prevents 6-OHDA-induced death of TH-positive neurons in the SNc in a 6-OHDA mouse model of Parkinson's disease (PD) . TXB4 can be used in neurodegenerative diseases, acute brain and spinal cord injury, and depression research[1].
12352203
Transferrin Receptor
Apoptosis
Neuroscience-Neurodegeneration
Neurological Disease
[TXB4]
[1]Clarke E, et al. A Single Domain Shark Antibody Targeting the Transferrin Receptor 1 Delivers a TrkB Agonist Antibody to the Brain and Provides Full Neuroprotection in a Mouse Model of Parkinson's Disease. Pharmaceutics. 2022 Jun 24;14 (7) :1335.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991380/
Inhibitory Antibodies
No Development Reported
Beschrijving
TXB4 is a brain-permeable human monoclonal antibody (mAb) targeting CD71. TXB4 prevents 6-OHDA-induced death of TH-positive neurons in the SNc in a 6-OHDA mouse
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