TYR-antilichaam

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.

7299

P14679

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 20-340 of human TYR (NP_000363.1) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

Mouse craniofacial

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 80kDa

IgG

TYR

Mouse liver

Tyrosinase

Homo sapiens

TYR, OCA1A, OCAIA, ATN, CMM8, OCA1, SHEP3

WB, IHC, IF

Liquid