Tyrosinase (TYR) Mouse Monoclonal Antibody [Kloon ID: LBI1F3]

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]

Carrier-free (BSA/glycerol-free) TYR mouse monoclonal antibody, clone LBI1F3

ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3

Homo sapiens tyrosinase (TYR), mRNA.

7299

P14679

Unconjugated

Melanogenesis, Metabolic pathways, Riboflavin metabolism, Tyrosine metabolism

Melanogenesis, Metabolic pathways, Riboflavin metabolism, Tyrosine metabolism

WB 1:2000, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Transmembrane

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

TYR

https://www.ncbi.nlm.nih.gov/gene/?term=7299

https://www.uniprot.org/uniprot/P14679