TYW3 Antilichaam

TYW3 Antibody: TYW3 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.

127253

Q6IPR3

Q6IPR3

Human, Mouse

Unconjugated

Primary Antibodies

Homeostasis

TYW3 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1203 - A549 Cell Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (94%), Pig: (94%)

TYW3 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TYW3 antibody can be stored at 4 ˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

TYW3 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW3 are known to exist; this antibody will detect both isoforms.

TYW3

TRNA-yW synthesizing protein 3 homolog (S. cerevisiae)

Homo sapiens

Noma A and Suzuki T. Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis. Nucleic Acids Symp. Ser. (Oxf) 2006; 65-6.

Noma A, Kirino Y, Ikeuchi Y, et al. Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA. EMBO J. 2006; 25:2142-54

TYW3 Antibody: C1orf171, C1orf171, tRNA wybutosine-synthesizing protein 3 homolog, tRNA-yW-synthesizing protein 3

ELISA, WB

42734381

Liquid