UACA Antibody - C-terminal regio : HRP (ARP62098 P050-HRP)

Uveal autoantigen with coiled-coil domains and ankyrin repeats

NUCLING

55075

Q9BZF9

NP_001008225

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

UACA regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. It promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. It regulates the redistribution of APAF1 into the nucleus after proapoptotic stress and down-regulates the expression of LGALS3 by inhibiting NFKB1.

KRT40; FUS; RNF2; HIF1AN; PAN2; TP63; UBC; USP48; RABEP1; STAMBP; FBXO25; NRD1; Mprip; MED14; CELSR3

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 85%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 85%; Rabbit: 92%; Rat: 85%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

154kDa

Wet Ice

1403

UACA

UACA

Rabbit

Uveal autoantigen with coiled-coil domains and ankyrin repeats

NM_001008224

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