Ub4ix

2396736-46-0

Proteasome, Apoptosis, DUB

DNA Damage/DNA Repair, Apoptosis, Ubiquitination, Proteases/Proteasome, Cell Cycle/Checkpoint

Ub4ix, a DUB/26S proteasome inhibitor, safeguards K48-linked Ub chains against cleavage by deubiquitinating enzymes (DUBs) and inhibits the proteasomal degradation of Ub-tagged proteins. Additionally, it diminishes the viability of Hela cells and triggers apoptosis, exhibiting an IC 50 value of 1.6 μM.

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C84H106N18O23S

1767.91

Ice Packs

-20°C