Ube1L (UBA7) Mouse Monoclonal Antibody [Kloon ID: LBI2B6]

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML) /retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) UBA7 mouse monoclonal antibody, clone LBI2B6

D8; UBA1B; UBE1L; UBE2

Homo sapiens ubiquitin like modifier activating enzyme 7 (UBA7), mRNA.

7318

P41226

Unconjugated

Parkinson's disease, Ubiquitin mediated proteolysis

Parkinson's disease, Ubiquitin mediated proteolysis

WB 1:500~2000, IHC 1:500

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

UBA7

https://www.ncbi.nlm.nih.gov/gene/?term=7318

https://www.uniprot.org/uniprot/P41226