UBE2E1 Antilichaam - middengebied: Biotine (ARP43012 P050-Biotine)

Ubiquitin-conjugating enzyme E2E 1

UBCH6

7324

P51965

NP_003332

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human UBE2E1

UBE2E1 catalyzes the covalent attachment of ubiquitin to other proteins. UBE2E1 mediates the selective degradation of short-lived and abnormal proteins.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

TRIM33; RNF11; TRIM32; UBC; TRAF6; MID1; TRIM23; XIAP; NHLRC1; ZNRF1; JADE1; RNF26; SLX8; SLX5; MARCH7; UBE2E1; MARCH5; RNF167; UBA1; RNF130; USP7; NEDD4; Rag1; ZNF827; PARK2; BRCA1; RNF122; RNF128; ITCH; TRIM39; RNF20; FBXO2; WWP2; STUB1; TOPORS; TRIM28

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

21kDa

Hong, S., (2008) Biochem. Biophys. Res. Commun. 371 (2), 256-260

Wet Ice

193

UBE2E1

UBE2E1

Rabbit

Ubiquitin-conjugating enzyme E2 E1

NM_003341

PKGDNIYEWRSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIY