UBE2E3 Antilichaam - N-terminaal gebied: Biotine (ARP43070_P050-Biotine)

Ubiquitin-conjugating enzyme E2E 3

UBCH9, UbcM2

10477

Q969T4

NP_006348

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2E3

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

RNF185; MUL1; TRIM39; RNF5; MID1; RNF25; MARCH5; UBE2E3; UBA1; TARDBP; UBC; HTT; ITCH; HERC4; NEDD4L; WWP2; RNF14; RNF8; MDM2; BRCA1; BARD1; KLHL42; RCBTB1; CUL1; CUL3; CUL4A; SPOP; ATXN1; ARID3A; RCBTB2; MOT2; CNOT4; NFE2L2; MID2; TRIM38; TRIM27; TRIM37

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

23kDa

Wet Ice

207

UBE2E3

UBE2E3

Rabbit

Ubiquitin-conjugating enzyme E2 E3

NM_006357

MSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERKPSATQQKKNTK