UBE2K Antilichaam

The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.

3093

P61086

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBE2K (NP_005330.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Neuroscience

Affinity purification

22Rv1

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 22kDa

IgG

WB: 1:500 - 1:2000

UBE2K

SKOV3

SW480

HL-60

Raji

U-251MG

Ubiquitin-conjugating enzyme E2K

Homo sapiens

UBE2K, DKFZp564C1216, DKFZp686J24237, E2-25K, HIP2, HYPG, LIG, UBC1

WB

Liquid