UBE2V1 Antilichaam - N-terminal regio : HRP (ARP61717 P050-HRP)

Ubiquitin-conjugating enzyme E2 variant 1

CIR1, UEV1, CROC1, UBE2V, UEV-1, UEV1A, CROC-1

7335

Q13404

NP_068823

Human

Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

UBC; TRAF6; ube2nb; UBQLN1; FAM168A; TRAF3IP2; STUB1; PARK2; TXNDC5; YWHAQ; ECHS1; YWHAZ; YWHAG; TGM2; LDHB; SFN; G6PD; IQCB1; PELI3; ULK4; POMP; UBXN7; UBE2C; AHCYL1; SSSCA1; UBE4B; TTC9C; ATP6V1G1; ATP6V1F; ZYX; UGDH; UCHL3; UBE2V2; UBE2N; UBE2D2; UBE2B

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

19kDa

Wet Ice

170

UBE2V1

UBE2V1

Rabbit

Ubiquitin-conjugating enzyme E2 variant 1

NM_021988

GEVQASYLKSQSKLSDEGRLEPRKFHCKGVKVPRNFRLLEELEEGQKGVG