UBE3C Antilichaam - N-terminaal gebied: Biotine (ARP43163_P050-Biotine)

Ubiquitin protein ligase E3C

HECTH2

9690

Q15386-3

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N-terminal region of Human UBE3C

E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. UBE3C can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. It has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.

UBC; GOLGA2; PSMD14; SHFM1; UBE2D1; PSMD2; PSMC5; PANK4; EEF2K; WDR92; TLK1; MTA2; ECT2; CPEB4; THOC7; RBM15; THOC2; WDR74; KDM1A; USP13; UTRN; PHKA2; APP; UBE2L3; UBE3C; PSMA2; ELAVL1; RAD21; MYC; CAND2; PSMD6

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

44kDa

Wet Ice

404

UBE3C

UBE3C

Rabbit

Ubiquitin-protein ligase E3C

MFSFEGDFKTRPKVSLGGASRKYSIQRSAFDRCATLSQSGGAFPIANGPN