UBIAD1 Antilichaam

The UbiA prenyltransferase domain containing 1 (UBIAD1) protein , also known as TERE1, was initially identified as a down-regulated gene in transitional cell carcinoma of the bladder (1) . Recently it has been shown to bind the cholesterol carrier APOE and modulate cellular cholesterol levels (2) . Mutations in the UBIAD1 gene can cause Schnyder crystalline corneal dystrophy, an autosomal dominant disease characterized by progressive opacification of the cornea resulting from the local accumulation of lipids (3) .

29914

Q9Y5Z9

NP_037451

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

UBIAD1 antibody is affinity chromatography purified via peptide column.

Cat. No. 1404 - Mouse Liver Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Chicken: (87%)

UBIAD1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

UBIAD1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

UBIAD1 antibody is human, mouse and rat reactive.

UBIAD1

UbiA prenyltransferase domain containing 1

Homo sapiens

McGarvey TW, Nguyen T, Tomaszewski JE, et al. Isolation and characterization of TERE1 gene, a gene down-regulated in transitional cell carcinoma of the bladder. Oncogene 2001; 20:1042-51.

Fredericks WJ, McGarvey T, Wang H, et al. The bladder tumor suppressor protein TERE1 (UBIAD1) modulates cell cholesterol: implications for tumor progression. DNA Cell Biol. 2011; 30:851-64.

Orr A, Dube MP, Marcadier J, et al. Mutations in the UBIAD1 gene, encoding a potential prenyltransferase, are causal for Schnyder crystalline corneal dystrophy. PLoS One 2007; 2:e685.

UBIAD1 Antibody: SCCD, TERE1, UbiA prenyltransferase domain-containing protein 1, Transitional epithelial response protein 1

ELISA, WB, IHC-P, IF

7019551

Liquid