UCP1 Antilichaam

The mitochondrial brown fat uncoupling protein 1 (UCP1) is a member of the family of mitochondrial anion carrier proteins (MACP) (1) . UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells (1) . UCP1 is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat (1) .

7350

P25874

NP_068605

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Obesity

UCP1 antibody is affinity chromatography purified via peptide column.

Cat. No. 1303 - Human Brain Tissue Lysate

1 mg/mL

UCP1 antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

UCP1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

UCP1 antibody is human, mouse and rat reactive.

UCP1

Cat. No. 10-201 - Human Liver Tissue Slide

Uncoupling protein 1 (mitochondrial, proton carrier)

Homo sapiens

Rial E, Gonzalez-Barroso MM, Fleury C, et al. The structure and function of the brown fat uncoupling protein UCP1: current status. Biofactors 1998; 8:209-19.

UCP1 Antibody: UCP, SLC25A7, UCP, Mitochondrial brown fat uncoupling protein 1, Solute carrier family 25 member 7, UCP 1

ELISA, WB, IHC-P

11225256

Liquid