UFD1 Antilichaam - middengebied: HRP (ARP59424 P050-HRP)

Ubiquitin recognition factor in ER associated degradation 1

UFD1L

7353

Q92890

NP_005650

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human UFD1L

The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.

HUWE1; YOD1; VCP; UBC; SHFM1; SUZ12; BTRC; EZH2; PDCD4; NPLOC4; NFKBIA; NUB1; NEDD8; CAV1; ADRB2; FAF1; TXLNA; UNC45A; VPS33B; UBE3A; UBE2N; PSMD7; SPRTN; UBXN6; GZMK; ERLIN2; ITPR1; PPHLN1; ANAPC2; TIAM2; TAF1C; TP53; SNX1; MASP1; PIK3CA; NGFR; IGHM; F13

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

UFD1L is supported by BioGPS gene expression data to be expressed in MCF7

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

34kDa

Wet Ice

307

UFD1

UFD1

Rabbit

Ubiquitin recognition factor in ER-associated degradation protein 1

NM_005659

NYNEKIYELRVMETKPDKAVSIIECDMNVDFDAPLGYKEPERQVQHEEST