UGT1A10 Antilichaam

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.

54575

Q9HAW8

Human

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human UGT1A10 (NP_061948.1) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

LO2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 60kDa

IgG

WB: 1:500 - 1:2000

UGT1A10

293T

A375

UDP glucuronosyltransferase family 1 member A10

Homo sapiens

GNT1, UDPGT, UGT-1A, UGT-1J, UGT1, UGT1-01, UGT1-1UGT1.1, UGT1.1UGT1A, UGT1A1, UGT1J, hUG-BR1, UDP-glucuronosyltransferase 1-1Bilirubin-specific UDPGT isozyme 1, UDP glucuronosyltransferase 1 family, polypeptide A1UDP glycosyltransferase 1 family, polypeptide A1UDP-glucuronosyltransferase 1-1, UDP-glucuronosyltransferase 1-A, UDP-glucuronosyltransferase 1-J, UDP-glucuronosyltransferase 1A1, UDP-glucuronosyltransferase 1A1UDPGT 1-1, UDPGT 1-10

WB

Liquid