UHRF1 Antilichaam - C-terminaal gebied: Biotine (ARP32596 P050-Biotine)

Ubiquitin-like with PHD and ring finger domains 1

Np95, hNP95, ICBP90, RNF106, TDRD22, hUHRF1, huNp95

29128

Q96T88

Human

The immunogen is a synthetic peptide directed towards the C-terminal region of Human UHRF1

This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.

UBC; H3F3B; H3F3A; HIST2H3D; HIST2H3A; HIST2H3C; UHRF1; HIST1H3F; HIST1H3B; HIST1H3E; HIST1H3C; HIST1H3D; HIST1H3A; HIST3H3; DNMT1; PARP1; PARP2; RNF2; USP7; KAT5; MPG; BTRC; CUL1; ZPR1; RB1; PRKACA; PML; SUV39H1; EZH2; SUZ12; UHRF2; USP11; HDAC1; ELAVL1

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

90kDa

Wet Ice

793

UHRF1

UHRF1

Rabbit

E3 ubiquitin-protein ligase UHRF1

DDEPGPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQ