UHRF2 Antilichaam

This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.

115426

Q96PU4

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 441-622 of human UHRF2 (NP_690856.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle

Affinity purification

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

IgG

UHRF2

Ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase

Homo sapiens

UHRF2, NIRF, URF2, RNF107, RP11-472F14.2

WB, IHC, IF

Liquid