UK-371800
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
UK-371800 is a highly selective PDE5 inhibitor (IC50 = 4.2 nM) . UK-371800 has good permeability and is not affected by the efflux of P-glycoprotein[1].
247582-13-4
12352005
Phosphodiesterase (PDE)
Metabolic Enzyme/Protease
Others
O=C1C2=NN(C)C(CC)=C2NC(C3=CC(S(=O)(N4CCN(CC)CC4)=O)=CN=C3O[C@H](C)COC)=N1
C23H33N7O5S
519.62
[1]Bunnage ME, et al. Highly potent and selective chiral inhibitors of PDE5: an illustration of Pfeiffer's rule. Bioorg Med Chem Lett. 2008 Dec 1;18 (23) :6033-6.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19446/
Reference compound1
Phase 1
PDE5
Beschrijving
UK-371800 is a highly selective PDE5 inhibitor (IC50 = 4.2 nM) . UK-371800 has good permeability and is not affected by the efflux of P-glycoprotein[1].
Specificaties
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