ULBP1 (NM 025218) Humaan Recombinant Proteïne

The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

Purified recombinant protein of Human UL16 binding protein 1 (ULBP1), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

N2DL-1; NKG2DL1; RAET1I

80329

Q9BZM6

NM_025218

6q25.1

E. coli

N-GST and C-His

Natural killer cell mediated cytotoxicity

Natural killer cell mediated cytotoxicity

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Druggable Genome, Transmembrane

55.8 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

ULBP1

Human

NP_079494

https://www.ncbi.nlm.nih.gov/gene/80329

https://www.uniprot.org/uniprot/Q9BZM6

https://www.ncbi.nlm.nih.gov/nuccore/NM_025218

https://www.ncbi.nlm.nih.gov/nuccore/NP_079494