Ulixertinibhydrochloride
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1956366-10-1
BVD-523 hydrochloride, VRT752271 hydrochloride
C04456-5mg
ERK
MAPK
Ulixertinib hydrochloride (BVD-523 hydrochloride, VRT752271 hydrochloride) is a highly selective, ATP-competitive, and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. It also reduces A375 cell proliferation with an IC50 of 180 nM and inhibits phosphorylated ERK (pERK) and the downstream kinase RSK (pRSK) in the A375 melanoma cell line, with IC50 values of 4.1 μM and 0.14 μM, respectively.
Beschrijving
Ulixertinibhydrochloride Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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