UMPS Antilichaam - C-terminalgebied: Biotine (ARP48147_P050-Biotine)

Uridine monophosphate synthetase

OPRT

7372

P11172

NP_000364

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast

The immunogen is a synthetic peptide directed towards the C terminal region of human UMPS

OPRT (UMPS) is involved in early events of pancreatic and gallbladder carcinogenesis and invasion of hepatocellular carcinomas. Orotate phosphoribosyltransferase is involved in the invasion and metastasis of colorectal carcinoma. Determination of OPRT levels in gastric carcinoma tissue enables to predict the response to S-1-based neoadjuvant/adjuvant chemotherapy.

UBC; CALU; PLA2G12A; ZNF227; RPS29; PAXIP1; PSEN1; NOS3; APRT; A2M; CUL3; USP50; CDC42EP3; DLST

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

UMPS is strongly supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 93%; Yeast: 75%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

52kDa

Sakamoto, E., (2007) Biochem. Biophys. Res. Commun. 363 (1), 216-222

Wet Ice

480

UMPS

UMPS

Rabbit

Uridine 5'-monophosphate synthase

NM_000373

VGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDII