UNC1999
Gecertificeerd

UNC1999

Catalog #: C12495-01
Maat: 5 mg
Droogijs Vereist

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

CAS Number

1431612-23-5

SKU

C12495-5mg

Target

Histone Methyltransferase

Applications

Epigenetics

Smiles

CCCC1=C (C (=O) NC (=C1) C) CNC (=O) C2=C3C=NN (C3=CC (=C2) C4=CN=C (C=C4) N5CCN (CC5) C (C) C) C (C) C

Molecular Formula

C33H43N7O2

Additionnal Information

UNC1999 is a potent, orally bioavailable and selective inhibitor of EZH2 and EZH1 with IC50 of 2 nM and 45 nM in cell-free assays, respectively, showing >1000-fold selectivity over a broad range of epigenetic and non-epigenetic targets. UNC1999 is a potent autophagy inducer. UNC1999 specifically suppresses H3K27me3/2 and induces a range of anti-leukemia effects including anti-proliferation, differentiation, and apoptosis.

Storage Conditions

2 years -80 in solvent

Beschrijving

UNC1999 Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamUNC1999
Categorie
Beschikbare grootte5 mg
CatalogusnummerC12495-01