UNC5B-antilichaam

This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.

219699

Q8IZJ1

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 290-377 of human UNC5B (NP_734465.2) .

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle, Neuroscience, Signal Transduction

Affinity purification

U-87MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 104kDa

IgG

UNC5B

A-549

293T

Mouse brain

Mouse lung

Mouse kidney

Unc-5 homolog B (C. elegans)

Homo sapiens

6330415E02Rik, A630020F16, D10Bwg0792e, netrin receptor UNC5B, protein unc-5 homolog 2, protein unc-5 homolog B, unc5 homolog 2, unc-5 homolog 2, unc-5 homolog B (C. elegans), Unc5b, Unc5h2 , P53RDL1, UNC5H2, UNQ1883/PRO4326

WB, IF

Liquid